Bruker Autoflex Speed MALDI TOF-TOF Mass Spectrometer
Matrix-assisted laser desorption ionization (MALDI) is a mass spectrometry technique used to determine the identity of a large range of molecules including DNA chains, proteins, large organic molecules, and fragile polymers that would be destroyed by other mass spectrometry techniques. MALDI analysis is especially important for biological applications since it can analyze very low concentrations and is the main instrument used in proteomics and polymer material analysis.
Bruker Maxis Impact HD Q-TOF Mass Spectrometer
Liquid Chromatography High-resolution Mass Spectrometry (LC-HRMS) is a tandem technique that combines chromatography to separate chemical mixtures and mass spectrometry to identify and quantify chemical compounds. This form of analysis has wide applicability to chemistry and biochemistry and is routinely employed in pharmaceutical industry, food and environmental analysis, and for proteomic and metabolomic applications. The high-resolution mass spectrometer (HRMS) component of this instrument aids in identifying chemical compounds by providing accurate mass data that is used to elucidate the identity and quantity of elements present in a molecule.
So how does a Mass Spectrometer work?
Some of the following sites prove useful in understanding how this machine works, and how we plan on using it for our research: https://www.bruker.com/products/mass-spectrometry-and-separations/maldi-toftof/autoflex/overview.html
https://www.physics.uci.edu/~
Here is a link to an interesting simulation: https://
The following websites were provided by Dr. McColgan regarding using the MALDI instrument to study hair samples for corn:
(m/z) = (2eU/L^2)*t^2
Where
m = Mass
z = Charge
e = Elementary Charge
U = Acceleration Voltage
L = Path Length
t = Time
List of SAInT Center Instruments at:
https://www.siena.edu/centers-institutes/saint-center/instrumentation-of-the-saint-center/#sthash.NQBMuMPv.dpuf
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